The Potential Risks of Consuming Monosodium Glutamate (MSG): Unveiling Scientific Evidence

Monosodium glutamate (MSG) is a flavor enhancer commonly used in food preparation, particularly in Asian cuisine. Despite its widespread use, concerns have been raised about its potential health risks. This article aims to explore the scientific evidence surrounding the potential risks of consuming MSG and provide a balanced view on its safety.

What is Monosodium Glutamate (MSG)?

MSG is a sodium salt of the naturally occurring non-essential amino acid, glutamic acid. It is used in the food industry as a flavor enhancer because it balances, blends, and rounds the perception of other tastes. It is commonly found in processed foods such as canned vegetables, soups, and processed meats.

The “Chinese Restaurant Syndrome”

The controversy surrounding MSG began in the 1960s when a condition known as “Chinese Restaurant Syndrome” was reported. Symptoms included numbness, flushing, heart palpitations, and general weakness. However, numerous scientific studies have failed to establish a definitive link between MSG and these symptoms. The U.S. Food and Drug Administration (FDA) has classified MSG as a food ingredient that is “generally recognized as safe”.

Scientific Studies on MSG

Several scientific studies have been conducted to investigate the potential risks of consuming MSG. Some studies have suggested a possible link between MSG and conditions such as obesity and metabolic disorders. However, these studies often rely on animal models or high doses of MSG, which do not accurately reflect typical human consumption.

Other studies have found no evidence of harm from MSG. A comprehensive review published in the Journal of the American Academy of Nurse Practitioners in 2006 concluded that MSG is safe for most people when “eaten at customary levels”.

Individual Sensitivity to MSG

While MSG is generally safe for the majority of people, some individuals may have a sensitivity to it. These individuals may experience symptoms such as headache, flushing, and sweating after consuming foods containing MSG. However, these reactions are usually mild and do not require medical treatment.


Based on current scientific evidence, MSG is generally safe for most people when consumed in moderate amounts. However, individuals who are sensitive to MSG should avoid it. As with any food ingredient, moderation is key. If you are concerned about MSG in your diet, it is always a good idea to read food labels and choose fresh, unprocessed foods whenever possible.


  • Freeman, M. (2006). Reconsidering the effects of monosodium glutamate: a literature review. Journal of the American Academy of Nurse Practitioners, 18(10), 482-486.
  • U.S. Food and Drug Administration. (2018). Questions and Answers on Monosodium glutamate (MSG). Retrieved from